1) to tire down with toil, exhaust with labour
1a) to afflict or oppress with evils
1b) to make trouble for
1c) to treat roughly
Part of Speech: verb
From G2596 and a derivative of G4192; to labor down, that is, wear with toil (figuratively harass): - oppress, vex.
These two sites give similar information, with the definition from several dictionaries and statistics on the use of the word.
Perseus Digital Library
University of Chicago's Logion lexicon
Thayer's dictionary plus other information.
From this site's dictionary (in Italian)
Click on the first column to search for that word as a form of the root καταπονέω; click on the second column to search for that grammatical form of the root καταπονέω; click on the third column to search for that word and grammatical form; click on the total to search for the root καταπονέω.