1) to make sorrowful
2) to affect with sadness, cause grief, to throw into sorrow
3) to grieve, offend
4) to make one uneasy, cause him a scruple
Part of Speech: verb
Citing in TDNT: 4:313, 540
From G3077; to distress; reflexively or passively to be sad: - cause grief, grieve, be in heaviness, (be) sorrow (-ful), be (make) sorry.
These two sites give similar information, with the definition from several dictionaries and statistics on the use of the word.
Perseus Digital Library
University of Chicago's Logion lexicon
Thayer's dictionary plus other information.
From this site's dictionary (in Italian)
Click on the first column to search for that word as a form of the root λυπέω; click on the second column to search for that grammatical form of the root λυπέω; click on the third column to search for that word and grammatical form; click on the total to search for the root λυπέω.