1) very sad, exceedingly sorrowful
2) overcome with sorrow so much as to cause one's death
Part of Speech: adjective
Citing in TDNT: 4:323, 540
From G4012 and G3077; grieved all around, that is, intensely sad: - exceeding (very) sorry (-owful).
These two sites give similar information, with the definition from several dictionaries and statistics on the use of the word.
Perseus Digital Library
University of Chicago's Logion lexicon
Thayer's dictionary plus other information.
From this site's dictionary (in Italian)
Click on the first column to search for that word as a form of the root περίλυπος; click on the second column to search for that grammatical form of the root περίλυπος; click on the third column to search for that word and grammatical form; click on the total to search for the root περίλυπος.