1) to skin, flay
2) to rend, mangle
2a) to vex, trouble, annoy
2b) to give one's self trouble, trouble one's self
Part of Speech: verb
Apparently a primary verb; to flay, that is, (figuratively) to harass: - trouble (self).
These two sites give similar information, with the definition from several dictionaries and statistics on the use of the word.
Perseus Digital Library
University of Chicago's Logion lexicon
Thayer's dictionary plus other information.
From this site's dictionary (in Italian)
Click on the first column to search for that word as a form of the root σκύλλω; click on the second column to search for that grammatical form of the root σκύλλω; click on the third column to search for that word and grammatical form; click on the total to search for the root σκύλλω.